Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27422669 | 0.83 | CYP2A6 (0.40) | ADORA2BEP300KAT2BDRD2 | |
| SCHEMBL27397709 | 0.67 | ALDH1A1 (0.43) | ADORA2BHDAC8GLABLM | |
| SCHEMBL9409708 | 0.66 | ADORA2B (0.42) | ADORA2BGLABLM | |
| SCHEMBL26926255 | 0.66 | HSD17B13 (0.50) | ADORA2B | |
| SCHEMBL27686738 | 0.65 | NOTUM (0.40) | HDAC8 | |
| SCHEMBL27275449 | 0.65 | TBXAS1 (0.36) | HDAC8DRD2 | |
| SCHEMBL7825229 | 0.64 | DRD2 (0.57) | DRD2 | |
| SCHEMBL16364103 | 0.61 | CHKA (0.52) | — | |
| SCHEMBL3561936 | 0.60 | CA12 (0.50) | BCHEEP300KAT2BBLM | |
| SCHEMBL29683214 | 0.60 | BCHE (0.43) | BCHEEP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1043990-C | Imidazolidinone derivative, acid-addition salt therefor, and remedy for senile dementia | KYORIN SEIYAKU KK (JP) | 1999-07-07 | — | — | CN | disclosed |
| CN-1135215-A | Imidazolidinone derivative, acid-addition salt therefor, and remedy for senile dementia | KYORIN SEIYAKU KK (JP) | 1996-11-06 | — | — | CN | disclosed |