Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429280 | 0.75 | ERN1 (0.34) | ERN1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL27608116 | 0.71 | PPARG (0.45) | ALDH1A1ACHEGAATSHRTDP1 | |
| SCHEMBL6557136 | 0.70 | POLB (0.41) | ERN1ALDH1A1SMN1; SMN2ACHETSHR | |
| SCHEMBL27916446 | 0.69 | ERN1 (0.41) | ERN1ALDH1A1SMN1; SMN2LMNAUSP2 | |
| SCHEMBL12269966 | 0.69 | ALDH1A1 (0.44) | ERN1ALDH1A1SMN1; SMN2ACHEGAA | |
| SCHEMBL11436443 | 0.66 | ACHE (0.54) | ERN1ALDH1A1SMN1; SMN2ACHEGAA | |
| SCHEMBL415683 | 0.65 | ERN1 (0.57) | ERN1ALDH1A1SMN1; SMN2ACHEKDM4E | |
| SCHEMBL11754484 | 0.64 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2ACHEGAAKDM4E | |
| SCHEMBL8699353 | 0.64 | ERN1 (0.47) | ERN1ALDH1A1SMN1; SMN2ACHEKDM4E | |
| SCHEMBL26090280 | 0.64 | BCHE (0.38) | ACHEGAATSHRNPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107158-A | Polysubstituted 2-amino-thiazole derivatives | SANOFI ELF (FR) | 1995-08-23 | — | — | CN | disclosed |