SCHEMBL27428201

SCHEMBL27428201

CCOC1(OCC)CN(c2ccccc2)CCO1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
CHRNA7 P36544 2/20 0.40
DRD2 P14416 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
CYP3A4 P08684 3/20 0.38
HIF1A Q16665 2/20 0.38
CYP2C19 P33261 4/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36
CYP2C9 P11712 1/20 0.36
AKR1C3 P42330 1/20 0.36
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
MAPT P10636 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27406182 0.86 LMNA (0.39) LMNACHRNA7DRD2SIGMAR1CYP3A4
SCHEMBL9975646 0.75 LMNA (0.46) LMNACHRNA7DRD2SIGMAR1CYP3A4
SCHEMBL18436319 0.74 LMNA (0.52) LMNACHRNA7CYP3A4HIF1ACYP2C19
SCHEMBL27621709 0.68 CYP2C19 (0.47) LMNACYP3A4HIF1ACYP2C19ALDH1A1
SCHEMBL28988333 0.68 LMNA (0.41) LMNACHRNA7DRD2ALDH1A1MAPT
SCHEMBL17319082 0.65 SIGMAR1 (0.61) LMNADRD2SIGMAR1TSHRMAPT
Ether SCHEMBL28195012 0.65 CHRNA7 (0.53) LMNACHRNA7DRD2SIGMAR1CYP3A4
Butanone SCHEMBL27655611 0.65 LMNA (0.63) LMNACHRNA7CYP2C19ALDH1A1CYP2C9
SCHEMBL254812 0.64 LMNA (0.95) LMNACHRNA7SIGMAR1CYP3A4CYP2C19
SCHEMBL3948094 0.64 LMNA (0.95) LMNACHRNA7SIGMAR1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1837958-B Planographic printing plate precursor and method of producing the same FUJI FILM CORP. (JP) 2011-12-28 CN disclosed
CN-100549826-C Multi-photon photoactivate system 3M INNOVATIVE PROPERTIES CO (US) 2009-10-14 CN disclosed
CN-100549823-C Multi-photon photoactivate method 3M INNOVATIVE PROPERTIES CO (US) 2009-10-14 CN disclosed
CN-1288498-C Multiphoton photosensitization system 3M INNOVATIVE PROPERTIES CO (US) 2006-12-06 CN disclosed
CN-1837958-A Planographic printing plate precursor and method of producing the same FUJI PHOTO FILM CO LTD (JP) 2006-09-27 CN disclosed
CN-1692313-A Multiphoton photosensitization method 3M INNOVATIVE PROPERTIES CO (US) 2005-11-02 CN disclosed
CN-1688938-A Multiphoton photosensitization system 3M INNOVATIVE PROPERTIES CO (US) 2005-10-26 CN disclosed
CN-1608230-A Multiphoton photosensitization system 3M INNOVATIVE PROPERTIES CO (US) 2005-04-20 CN disclosed
CN-1103698-C Lithographic form plate TORAY INDUSTRIES (JP) 2003-03-26 CN disclosed
CN-1152278-A Lithographic form plate TORAY INDUSTRIES (JP) 1997-06-18 CN disclosed