Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18436319 | 0.80 | LMNA (0.52) | LMNAFFAR2CHRNA7CYP2C19ALDH1A1 | |
| SCHEMBL27428201 | 0.75 | LMNA (0.43) | LMNACHRNA7DRD2SIGMAR1CYP2C19 | |
| SCHEMBL22642510 | 0.74 | SMN1; SMN2 (0.35) | FFAR2ALDH1A1MAPTKMT2A | |
| SCHEMBL27621709 | 0.73 | CYP2C19 (0.47) | LMNACYP2C19ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL9975643 | 0.71 | CHRNA7 (0.46) | CHRNA7DRD2SIGMAR1CYP2C19ALDH1A1 | |
| SCHEMBL27406182 | 0.71 | LMNA (0.39) | LMNACHRNA7DRD2SIGMAR1CYP2C19 | |
| SCHEMBL28988333 | 0.70 | LMNA (0.41) | LMNACHRNA7DRD2ALDH1A1MAPT | |
| SCHEMBL9975647 | 0.67 | CHRNA7 (0.53) | LMNACHRNA7DRD2SIGMAR1CYP2C19 | |
| Butanone SCHEMBL27655611 | 0.67 | LMNA (0.63) | LMNACHRNA7CYP2C19ALDH1A1MAPT | |
| SCHEMBL22857712 | 0.66 | CYP3A4 (0.50) | CHRNA7CYP2C19ALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8945725-B2 | Organic electroluminescence device | UDC IRELAND LIMITED (IE) | 2015-02-03 | — | — | US | disclosed |
| US-20120153816-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120153816-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | L1CAM, LAGE3, LEF1 | LMNA 1059/4885FFAR2 4864/4885CHRNA7 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.