Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 6/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7239669 | 0.80 | NPC1 (0.49) | CYP1A2ALDH1A1TSHRMAPK1LMNA | |
| SCHEMBL27427760 | 0.79 | TRPV1 (0.35) | KDM5AKDM4CKDM5BALDH1A1HPGD | |
| SCHEMBL27469144 | 0.79 | HRH4 (0.48) | KDM5AKDM4CALKBH1MAPK14CYP1A2 | |
| SCHEMBL27539537 | 0.73 | VNN1 (0.42) | ALDH1A1TSHRCLK4MAPK1 | |
| SCHEMBL27535631 | 0.72 | KDM5A (0.46) | KDM5AKDM4CKDM5BMAPK1HIF1A | |
| SCHEMBL3804975 | 0.68 | NPC1 (0.54) | ALDH1A1MAPK1HPGD | |
| SCHEMBL7229537 | 0.67 | MAPK1 (0.50) | KDM5AKDM4CALKBH1MAPK1CYP2C9 | |
| SCHEMBL18066391 | 0.66 | FFAR4 (0.50) | ALDH1A1MAPK1LMNACYP2C9CYP2C19 | |
| SCHEMBL28746011 | 0.65 | LMNA (0.39) | CYP1A2ALDH1A1TSHRLMNACYP2C19 | |
| SCHEMBL13403105 | 0.65 | L3MBTL1 (0.47) | KDM5AKDM4CCYP1A2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105707-C | Pyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2003-04-16 | — | — | CN | disclosed |
| CN-1251578-A | Pyrazole derivative | DAIICHI SEIYAKU CO (JP) | 2000-04-26 | — | — | CN | disclosed |