Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL827858 | 0.73 | CYP3A4 (0.53) | ALDH1A1RAB9ALMNA | |
| SCHEMBL8894531 | 0.73 | ACHE (0.43) | POLBALDH1A1LMNARECQLERN1 | |
| SCHEMBL7905410 | 0.73 | CYP3A4 (0.47) | POLBTDP1HPGDRECQL | |
| SCHEMBL27429276 | 0.72 | POLB (0.39) | POLBTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7894116 | 0.70 | PTGS2 (0.50) | KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9119401 | 0.69 | SYNJ2 (0.54) | POLBHPGDRECQL | |
| SCHEMBL7901522 | 0.68 | CYP3A4 (0.65) | TDP1KDM4EALDH1A1HPGDERN1 | |
| SCHEMBL8893819 | 0.68 | NPC1 (0.41) | CYP1A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL27729809 | 0.68 | POLB (0.41) | POLBTDP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL18210551 | 0.68 | LMNA (0.44) | POLBTDP1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656648-A | TREATMENT OF PATHOLOGIES NECESSITATING STIMULATION OF CHOLECYSTOKININ-A RECEPTORS BY TOTAL OR PARTIAL AGONIST EFFECT | SANOFI (FR) | 1997-08-12 | — | — | US | disclosed |
| EP-0611766-A1 | Polysubstituted 2-amido thiazoles derivatives, process for their preparation, pharmaceutical compositions and utilization for the preparation of a medicament | SANOFI (FR) | 1994-08-24 | — | — | EP | disclosed |