Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 4/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429703 | 0.96 | NPC1 (0.48) | BRAFNPC1RAB9AJAK3EGFR | |
| SCHEMBL27429699 | 0.80 | EGFR (0.51) | NPC1RAB9AJAK3EGFRSRC | |
| SCHEMBL27248325 | 0.79 | HPGD (0.54) | BRAFJAK3L3MBTL1 | |
| SCHEMBL27248330 | 0.79 | L3MBTL1 (0.58) | JAK3EGFRSRCL3MBTL1 | |
| SCHEMBL27248319 | 0.78 | HRH4 (0.46) | BRD4L3MBTL1 | |
| SCHEMBL27429695 | 0.78 | HRH4 (0.49) | L3MBTL1 | |
| SCHEMBL27429710 | 0.77 | HTR2C (0.64) | SRCBRD4 | |
| SCHEMBL27430722 | 0.76 | HTR2C (0.44) | SRCL3MBTL1 | |
| SCHEMBL27430646 | 0.75 | HRH4 (0.41) | BRAFSRCBRD4L3MBTL1 | |
| SCHEMBL27248311 | 0.75 | HPGD (0.58) | JAK3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |