Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | JAK3 | P52333 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429693 | 0.96 | BRAF (0.47) | NPC1RAB9AJAK3EGFRBRAF | |
| SCHEMBL27429699 | 0.83 | EGFR (0.51) | NPC1RAB9AJAK3EGFRSRC | |
| SCHEMBL27248330 | 0.82 | L3MBTL1 (0.58) | JAK3EGFRL3MBTL1SRCHTR2A | |
| SCHEMBL27248319 | 0.81 | HRH4 (0.46) | BRD4L3MBTL1HTR2AHTR2CCCND3 | |
| SCHEMBL27429695 | 0.81 | HRH4 (0.49) | L3MBTL1HTR2AHTR2CHRH4 | |
| SCHEMBL27429710 | 0.79 | HTR2C (0.64) | BRD4SRCHTR2AHTR2CCCNK | |
| SCHEMBL27430722 | 0.79 | HTR2C (0.44) | L3MBTL1SRCHTR2AHTR2CHRH4 | |
| SCHEMBL27430744 | 0.78 | HRH4 (0.41) | BRAFBRD4L3MBTL1SRCHTR2A | |
| SCHEMBL27430721 | 0.78 | HRH4 (0.41) | BRAFBRD4L3MBTL1SRCHTR2A | |
| SCHEMBL27248311 | 0.78 | HPGD (0.58) | JAK3L3MBTL1HTR2AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |