Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603733 | 0.82 | MAP2K3 (0.42) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL8012385 | 0.80 | ACHE (0.55) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL28595582 | 0.80 | CYP19A1 (0.54) | ADORA2AALDH1A1MAPTMEN1HPGD | |
| SCHEMBL29838670 | 0.80 | CYP19A1 (0.54) | ADORA2AALDH1A1MAPTMEN1HPGD | |
| SCHEMBL3121916 | 0.76 | ADORA1 (0.53) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL29852429 | 0.75 | KDM4E (0.52) | ALDH1A1MAPTMEN1HPGDKMT2A | |
| SCHEMBL4053052 | 0.74 | MAP2K3 (0.56) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL2873300 | 0.73 | ACHE (1.00) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL696285 | 0.73 | ACHE (0.56) | ACHEADORA2AADORA1ALDH1A1MAPT | |
| SCHEMBL4257668 | 0.73 | ADORA2A (0.67) | ACHEADORA2AADORA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108524-C | High-sensitivity detecting method for triamterenes compound | XUHUI DISTR CENTRAL HOSPITAL S (CN) | 2003-05-14 | — | — | CN | disclosed |