Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.68 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.48 |
| ▸ | PF4 | P02776 | 1/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.42 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 2/20 | 0.41 |
| ▸ | IFNG | P01579 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.40 |
| ▸ | BMP2 | P12643 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433393 | 0.92 | F10 (0.61) | F10HPSEPF4LGALS3F2 | |
| SCHEMBL26715952 | 0.89 | F10 (0.57) | F10HPSEPF4F2SERPINC1 | |
| SCHEMBL26715922 | 0.89 | F10 (0.57) | F10HPSEPF4F2SERPINC1 | |
| SCHEMBL27433373 | 0.86 | LGALS3 (0.56) | F10HPSELGALS3LGALS1LGALS7; LGALS7B | |
| SCHEMBL27432958 | 0.85 | F10 (0.51) | F10HPSELGALS3LGALS1LGALS7; LGALS7B | |
| SCHEMBL13483310 | 0.83 | LGALS3 (0.54) | F10HPSELGALS3LGALS1LGALS7; LGALS7B | |
| SCHEMBL25645147 | 0.82 | F10 (0.50) | F10HPSEPF4LGALS3F2 | |
| Fondaparinux SCHEMBL1650579 | 0.81 | F10 (1.00) | F10HPSEPF4F2SERPINC1 | |
| Fondaparinux SCHEMBL19619397 | 0.81 | F10 (1.00) | F10HPSEPF4F2SERPINC1 | |
| Fondaparinux SCHEMBL15296579 | 0.81 | F10 (1.00) | F10HPSEPF4F2SERPINC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216419-A1 | SULFATED OLIGOSACCHARIDES HAVING ANTI-INFLAMMATORY ACTIVITY | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216419-A1 | SULFATED OLIGOSACCHARIDES HAVING ANTI-INFLAMMATORY ACTIVITY | HMGB1, HPSE, HMGB2 | F10 1454/4885HPSE 2/4885PF4 2209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.