SCHEMBL27433393

SCHEMBL27433393

CO[C@H]1OC(CO)[C@@H](O[C@@H]2OC(C(=O)O)[C@@H](O[C@H]3OC(CO)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(CO)[C@@H](O[C@@H]6OC(C(=O)O)[C@@H](C)C(O)C6O)C(O)C5NS(=O)(=O)O)C(O)C4O)C(O)C3NS(=O)(=O)O)C(O)C2O)C(O)C1NS(=O)(=O)O

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 3/20 0.61
▸ HPSE Q9Y251 8/20 0.45
▸ FGF1 P05230 2/20 0.41
▸ IFNG P01579 1/20 0.41
▸ FGF2 P09038 1/20 0.41
▸ BMP2 P12643 1/20 0.41
▸ VEGFA P15692 1/20 0.41
▸ SFRP1 Q8N474 1/20 0.41
▸ PF4 P02776 1/20 0.40
▸ LGALS3 P17931 4/20 0.39
▸ F2 P00734 1/20 0.39
▸ SERPINC1 P01008 1/20 0.39
▸ PTN P21246 1/20 0.38
▸ MDK P21741 1/20 0.38
▸ BDNF P23560 1/20 0.38
▸ LGALS1 P09382 1/20 0.38
▸ LGALS7; LGALS7B P47929 1/20 0.38
▸ AMY2A P04746 1/20 0.37
▸ LGALS9 O00182 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27433388 0.92 F10 (0.68) F10HPSEFGF1IFNGFGF2
SCHEMBL26715952 0.89 F10 (0.57) F10HPSEFGF1IFNGFGF2
SCHEMBL26715922 0.89 F10 (0.57) F10HPSEFGF1IFNGFGF2
SCHEMBL13483313 0.87 LGALS3 (0.51) F10HPSEFGF1LGALS3PTN
SCHEMBL27433376 0.87 LGALS3 (0.51) F10HPSEFGF1LGALS3PTN
SCHEMBL27432972 0.86 F10 (0.46) F10HPSEFGF1IFNGFGF2
SCHEMBL13124074 0.84 LGALS8 (0.45) F10FGF1LGALS3LGALS1LGALS7; LGALS7B
SCHEMBL13483310 0.81 LGALS3 (0.54) F10HPSELGALS3PTNMDK
SCHEMBL25645147 0.81 F10 (0.50) F10HPSEFGF1IFNGFGF2
SCHEMBL27433011 0.80 FGF1 (0.55) F10FGF1LGALS3LGALS1LGALS7; LGALS7B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216419-A1 SULFATED OLIGOSACCHARIDES HAVING ANTI-INFLAMMATORY ACTIVITY THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216419-A1 SULFATED OLIGOSACCHARIDES HAVING ANTI-INFLAMMATORY ACTIVITY HMGB1, HPSE, HMGB2 F10 1454/4885HPSE 2/4885FGF1 1160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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