SCHEMBL27433477

SCHEMBL27433477

Cc1c(Cl)cc2c(c1Br)OCC(=O)N2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.44
PDE3A Q14432 2/20 0.44
MMP12 P39900 1/20 0.42
NR3C2 P08235 4/20 0.40
NR3C1 P04150 3/20 0.40
PGR P06401 3/20 0.40
PKM P14618 2/20 0.39
IL4I1 Q96RQ9 1/20 0.39
TP53 P04637 4/20 0.38
MAPT P10636 4/20 0.38
AR P10275 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
PARP1 P09874 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4100769 0.84 MMP12 (0.44) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL4290482 0.81 IL4I1 (0.44) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL21552045 0.79 PGR (0.42) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL20278370 0.78 PDE3B (0.55) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL4480236 0.76 PDE3B (0.41) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL4288420 0.76 PDE3B (0.47) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL17875671 0.76 PDE3B (0.43) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL8082246 0.73 PGR (0.46) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL4102430 0.72 PARP1 (0.44) PDE3BPDE3AMMP12NR3C2NR3C1
SCHEMBL8236302 0.71 IL4I1 (0.44) PDE3BPDE3AMMP12NR3C2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4630412-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2025-10-15 EP disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed
WO-2024121130-A1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2024-06-13 WO disclosed