Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433623 | 0.76 | MAPK14 (0.41) | ACHEMAPK14MEN1KMT2ATDP1 | |
| SCHEMBL27458146 | 0.67 | PDPK1 (0.32) | — | |
| SCHEMBL27458147 | 0.66 | MEN1 (0.39) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL14248561 | 0.61 | ACHE (0.44) | ACHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8706715 | 0.61 | TSHR (0.46) | MEN1KMT2ATDP1SLC6A2SLC6A4 | |
| SCHEMBL5045338 | 0.61 | ALDH1A1 (0.47) | ACHEMEN1KMT2AKDM4EMAPT | |
| SCHEMBL8121494 | 0.59 | ALDH1A1 (0.50) | MEN1KMT2ATSPOALDH1A1L3MBTL1 | |
| SCHEMBL3830101 | 0.59 | ALDH1A1 (0.44) | MAPK14MEN1KMT2AKDM4EHTT | |
| SCHEMBL5554925 | 0.58 | ALDH1A1 (0.43) | MEN1KMT2AMAPTHTTALDH1A1 | |
| SCHEMBL15215895 | 0.58 | POLB (0.49) | ACHEMEN1KMT2ATDP1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1123564-C | Anti-inflammatory compounds | ORTHO MCNEIL PHARMACEUTICAL CO (US) | 2003-10-08 | — | — | CN | claimed |
| CN-1249742-A | Anti-inflammatory compounds | ORTHO MCNEIL PHARMACEUTICAL CO (US) | 2000-04-05 | — | — | CN | claimed |