Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13498025 | 0.86 | MRGPRX4 (0.44) | MRGPRX4ALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL5936393 | 0.85 | ALDH1A1 (0.50) | MRGPRX4ALDH1A1MAPK1L3MBTL1KDM4E | |
| SCHEMBL10053141 | 0.84 | ALDH1A1 (0.58) | MRGPRX4ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL19245035 | 0.81 | MRGPRX4 (0.42) | MRGPRX4ALDH1A1L3MBTL1KDM4EPTGER3 | |
| SCHEMBL21805199 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1KDM4EHPGD | |
| SCHEMBL25760326 | 0.80 | IDO1 (0.52) | ALDH1A1MAPK1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL11703597 | 0.79 | MMP2 (0.54) | ALDH1A1MAPK1L3MBTL1KDM4EHPGD | |
| SCHEMBL1691249 | 0.78 | L3MBTL1 (0.43) | ALDH1A1MAPK1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL8006943 | 0.78 | AOC3 (0.50) | MRGPRX4ALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL14416816 | 0.78 | THRA (0.44) | ALDH1A1MAPK1L3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086744-A2 | COMPOSITIONS AND USES THEREOF | SOLVE THERAPEUTICS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |