Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954142 | 1.00 | CHRM5 (0.38) | CHRM5CHRM1CHRM3ENPP2PTGER3 | |
| SCHEMBL30954089 | 0.91 | ENPP2 (0.36) | CHRM5CHRM1CHRM3ENPP2LMNA | |
| SCHEMBL27434153 | 0.91 | ENPP2 (0.36) | CHRM5CHRM1CHRM3ENPP2LMNA | |
| SCHEMBL27435327 | 0.88 | DRD2 (0.40) | PTGER3LMNAHSD17B10KDM4E | |
| SCHEMBL27434015 | 0.88 | CHRM1 (0.37) | CHRM5CHRM1CHRM3PTGER3LMNA | |
| SCHEMBL30954157 | 0.88 | CHRM1 (0.37) | CHRM5CHRM1CHRM3PTGER3LMNA | |
| SCHEMBL30954129 | 0.86 | HTR4 (0.36) | CHRM5CHRM3ENPP2LMNAMAPT | |
| SCHEMBL27434031 | 0.86 | HTR4 (0.36) | CHRM5CHRM3ENPP2LMNAMAPT | |
| SCHEMBL30954122 | 0.85 | P2RX7 (0.36) | CHRM5CHRM3ENPP2GAA | |
| SCHEMBL30954098 | 0.85 | ENPP2 (0.37) | CHRM5CHRM3ENPP2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |