Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5562895 | 0.82 | CLK4 (0.59) | MAP4K4PLAUGRM5IDO1EGLN2 | |
| SCHEMBL3362125 | 0.80 | EGLN2 (0.50) | MAPKAPK2CYP11B2MAP4K4GRM5GSK3B | |
| SCHEMBL4027001 | 0.79 | IDO1 (0.55) | MAPKAPK2MAP4K4GSK3BIDO1CYP19A1 | |
| SCHEMBL18123834 | 0.79 | MMP3 (0.48) | CYP11B2MAP4K4MMP3PLAUKIF11 | |
| SCHEMBL222313 | 0.78 | — | — | |
| SCHEMBL29413268 | 0.78 | — | — | |
| SCHEMBL3500189 | 0.78 | MAP4K4 (0.49) | MAPKAPK2MAP4K4IDO1 | |
| SCHEMBL7016006 | 0.78 | GRM5 (0.53) | CYP11B2GRM5CYP11B1EGLN2 | |
| SCHEMBL3397985 | 0.78 | DYRK1A (0.54) | MAPKAPK2CYP11B2MAP4K4MMP3GSK3B | |
| SCHEMBL29432635 | 0.78 | DYRK1A (0.54) | MAPKAPK2CYP11B2MAP4K4MMP3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732109-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2017-08-15 | — | — | US | disclosed |
| EP-2247603-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-09-28 | — | — | EP | disclosed |
| US-9018363-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-28 | — | — | US | disclosed |
| US-9006468-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-03-19 | — | — | US | disclosed |
| CN-101998963-B | Insecticidal composition | DOW AGROSCIENCES LLC | 2014-09-24 | — | — | CN | disclosed |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2012-05-17 | — | — | US | disclosed |
| US-8178658-B2 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| CN-101998963-A | Insecticidal composition | DOW AGROSCIENCES LLC (US) | 2011-03-30 | — | — | CN | disclosed |
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209476-A1 | Insecticide (against arthropods), nematocide; use against pesticide-resistant pests; use on plants and animals; Compounds are tetrahydropyrans substituted with an aryl-heteroaryl-aryl-containing group | DDT, ACHE, NANP | MAPKAPK2 4198/4885CYP11B2 1981/4885MAP4K4 4393/4885 |
| US-20120172218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | MAPKAPK2 3870/4885CYP11B2 1884/4885MAP4K4 4597/4885 |
| US-20150080326-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | MAPKAPK2 3870/4885CYP11B2 1884/4885MAP4K4 4597/4885 |
| US-20120122805-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | MAPKAPK2 3870/4885CYP11B2 1884/4885MAP4K4 4597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.