Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 7/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27434847 | 0.83 | TAS1R3 (0.36) | MAPTTAS1R3TAS1R1TAS1R2DRD3 | |
| SCHEMBL27435327 | 0.83 | DRD2 (0.40) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL27432939 | 0.82 | MAPT (0.38) | MAPTTAS1R3TAS1R1TAS1R2DRD3 | |
| SCHEMBL27435508 | 0.79 | DRD3 (0.41) | MAPTDRD3DRD2KMT2ATP53 | |
| SCHEMBL27435244 | 0.78 | TP53 (0.43) | MAPTCYP1A2KMT2AKDM4ECYP2C19 | |
| SCHEMBL27435492 | 0.77 | CPT2 (0.32) | MAPTTAS1R3TAS1R1TAS1R2DRD3 | |
| SCHEMBL27435364 | 0.77 | KCNA3 (0.42) | DRD3DRD2DRD4KDM4EHTR1A | |
| SCHEMBL30954135 | 0.76 | POLB (0.44) | MAPTKMT2AKDM4EMAPK1MEN1 | |
| SCHEMBL30954110 | 0.76 | ENPP2 (0.37) | MAPTKMT2AKDM4EHSD17B10TP53 | |
| SCHEMBL30954108 | 0.75 | KDM4E (0.43) | MAPTTAS1R3TAS1R1TAS1R2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024121130-A1 | COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS | NMD PHARMA A/S (DK) | 2024-06-13 | — | — | WO | disclosed |