Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL929137 | 0.82 | KDM4E (0.54) | ALDH1A1KDM4EGLAGAABACE1 | |
| SCHEMBL27435847 | 0.81 | SRPK1 (0.49) | ALDH1A1KDM4EBACE1LMNA | |
| SCHEMBL9230751 | 0.77 | HTR6 (0.38) | BACE1HTR6 | |
| SCHEMBL22547352 | 0.76 | ALDH1A1 (0.48) | ALDH1A1BACE1LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL12527393 | 0.71 | KDM4E (0.55) | ALDH1A1KDM4EGLAGAABACE1 | |
| SCHEMBL24451857 | 0.70 | ALDH1A1 (0.45) | ALDH1A1BACE1CYP1A2HTR6POLB | |
| SCHEMBL20883777 | 0.70 | ALDH1A1 (0.45) | ALDH1A1BACE1HTR6POLB | |
| SCHEMBL9227997 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4EGLAGAABACE1 | |
| SCHEMBL7537046 | 0.69 | CHEK1 (0.54) | HTR6 | |
| SCHEMBL8992892 | 0.68 | ALDH1A1 (0.56) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105360-A | 1-[2H-1-benzopyran-2-one-8yl]-piperazin derivative | DUPHAR INT RES (NL) | 1995-07-19 | — | — | CN | disclosed |