Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229909 | 0.82 | KMT2A (0.48) | SRPK1ALDH1A1BACE1MEN1KMT2A | |
| SCHEMBL27434832 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EBACE1LMNA | |
| SCHEMBL7540788 | 0.75 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1KMT2ANPY2R | |
| SCHEMBL9229213 | 0.72 | KMT2A (0.57) | ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9228397 | 0.72 | DRD2 (0.53) | BACE1 | |
| SCHEMBL27412494 | 0.70 | BACE1 (0.54) | ALDH1A1BACE1LMNA | |
| SCHEMBL9227350 | 0.69 | DRD2 (0.50) | BACE1 | |
| SCHEMBL9230355 | 0.69 | KDM4E (0.61) | ALDH1A1KDM4EBACE1LMNA | |
| SCHEMBL9230826 | 0.69 | DRD2 (0.55) | BACE1KMT2A | |
| SCHEMBL27436549 | 0.69 | ALDH1A1 (0.48) | ALDH1A1KDM4EBACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1105360-A | 1-[2H-1-benzopyran-2-one-8yl]-piperazin derivative | DUPHAR INT RES (NL) | 1995-07-19 | — | — | CN | disclosed |