Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767959 | 0.90 | L3MBTL1 (0.60) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL6002470 | 0.84 | MAPT (0.73) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL4940284 | 0.84 | TDP1 (0.68) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL293916 | 0.83 | MAPT (0.72) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL11515701 | 0.83 | MAPT (0.72) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL17364440 | 0.82 | TSHR (0.70) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL13002357 | 0.81 | AKR1C3 (0.63) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL3272499 | 0.81 | MAPT (0.73) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL12786875 | 0.81 | FBP1 (0.59) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL7128152 | 0.80 | HPGD (0.66) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1262547-C | Phenyl-and aminophenyl-alkyl sulfonamide and urea derivative | HOFFMANN LA ROCHE (CH) | 2006-07-05 | — | — | CN | disclosed |
| CN-1176910-C | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives | - | 2004-11-24 | — | — | CN | disclosed |
| CN-1515559-A | Phenyl-and aminophenyl-alkyl sulfonamide and urea derivative | - | 2004-07-28 | — | — | CN | disclosed |
| CN-1515562-A | Phenyl-and aminophenyl-alkyl sulfonamide and urea derivative | - | 2004-07-28 | — | — | CN | disclosed |
| CN-1104422-C | Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 2003-04-02 | — | — | CN | disclosed |
| CN-1203228-A | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives | HOFFMANN LA ROCHE (CH) | 1998-12-30 | — | — | CN | disclosed |