Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | CASP7 | P55210 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167600 | 0.89 | TDP1 (0.79) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL16767959 | 0.88 | L3MBTL1 (0.60) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL12786875 | 0.88 | FBP1 (0.59) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL26468007 | 0.87 | TDP1 (0.77) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL7168043 | 0.84 | TDP1 (0.72) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL27434871 | 0.84 | MEN1 (0.68) | TDP1L3MBTL1ALDH1A1MAPK1MEN1 | |
| SCHEMBL2327163 | 0.82 | L3MBTL1 (0.56) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL14247885 | 0.82 | FBP1 (0.55) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL497223 | 0.82 | MAPK1 (0.74) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 | |
| SCHEMBL230292 | 0.81 | TDP1 (1.00) | TDP1L3MBTL1ALDH1A1MAPK1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A4, SLC6A2, SLC6A3 | TDP1 367/4885L3MBTL1 4326/4885ALDH1A1 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.