Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Oxazepam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALB | P02768 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | PGR | P06401 | 1/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.68 |
| ▸ | CCKBR | P32239 | 4/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazepam SCHEMBL29803925 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL13746803 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL9614141 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL528376 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL13746806 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL5498881 | 1.00 | LMNA (1.00) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL28100675 | 0.97 | LMNA (0.95) | LMNAMEN1ALBKMT2APGR | |
| Lorazepam SCHEMBL3695725 | 0.93 | LMNA (0.89) | LMNAMEN1ALBKMT2APGR | |
| SCHEMBL28348373 | 0.92 | LMNA (0.85) | LMNAMEN1ALBKMT2APGR | |
| Oxazepam SCHEMBL6680438 | 0.90 | LMNA (0.81) | LMNAMEN1ALBKMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27822 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624036-B2 | Method of treating post-traumatic stress disorder | INTRA-CELLULAR THERAPIES, INC. (US) | 2026-05-12 | — | — | US | claimed |
| US-12624037-B2 | Method of treating agitation, aggressive behavior, and impulse control disorder | INTRA-CELLULAR THERAPIES, INC. (US) | 2026-05-12 | — | — | US | claimed |
| WO-2026090360-A1 | FUSED PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC. (US) | 2026-04-30 | — | — | WO | claimed |
| US-20260108529-A1 | FUSED AMINO PYRIMIDINE COMPOUNDS FOR TREATMENT OF TINNITUS, ACUTE SENSORINEURAL HEARING LOSS, AGE-RELATED HEARING LOSS, AND MENIERE'S DISEASE | OVID THERAPEUTICS INC (US) | 2026-04-23 | — | — | US | claimed |
| EP-4729048-A1 | ORALLY DISPERSIBLE TABLETS OF OXAZEPAM | Neuraxpharm Pharmaceuticals, S.L. (ES) | 2026-04-22 | — | — | EP | claimed |
| US-12594388-B2 | Device to deliver a predetermined amount of a substance to a natural orifice of the body | APTARGROUP, INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-20260092932-A1 | METHODS AND COMPOSITIONS FOR THE DETECTION, DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDER | THE JOHNSON CENTER FOR CHILD HEALTH AND DEV (US) | 2026-04-02 | — | — | US | claimed |
| US-20260076953-A1 | METHODS OF DIAGNOSING AND TREATING ADHD IN BIOMARKER POSITIVE SUBJECTS | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-03-19 | — | — | US | claimed |
| US-20260028460-A1 | Erodible Film and Method of Making | VIPA PHARMA INC (US) | 2026-01-29 | — | — | US | claimed |
| EP-3507371-B1 | COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM | UNIV RUTGERS (US) | 2026-01-28 | — | — | EP | claimed |
| EP-0050487-A1 | Pharmaceutical compositions comprising a benzodiazepine drug and a phenanthridine derivative | PFIZER INC. (US) | 1982-04-28 | — | — | EP | claimed |
| US-4320124-A | ANALGESICS | PFIZER INC. (US) | 1982-03-16 | — | — | US | claimed |
| US-4316897-A | TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1982-02-23 | — | — | US | claimed |
| EP-0025546-A2 | Therapeutical use of tranquillizing benzodiazepine derivatives and mixtures containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-03-25 | — | — | EP | claimed |
| US-4207307-A | Simultaneous immunoassay of multiple antigens and assay for cocaine metabolites | RESEARCH CORPORATION (US) | 1980-06-10 | — | — | US | claimed |
| US-4175119-A | Composition and method to prevent accidental and intentional overdosage with psychoactive drugs | PORTER GARRY L | 1979-11-20 | — | — | US | claimed |
| US-4083948-A | IODINE LABELS | HOFFMANN-LA ROCHE, INC. (US) | 1978-04-11 | — | — | US | claimed |
| US-4065451-A | CNS DEPRESSANTS | AMERICAN HOME PRODUCTS (US) | 1977-12-27 | — | — | US | claimed |
| US-4028467-A | Analgesic compositions comprising levo-propoxyphene and benzo diazepine and process | BERGER FRANK M | 1977-06-07 | — | — | US | claimed |
| US-4028466-A | Analgesic compositions comprising dextro-propoxyphene and benzodiazepine and process | BERGER FRANK M | 1977-06-07 | — | — | US | claimed |