SCHEMBL27435402

SCHEMBL27435402

C=C(C)C1(C)Oc2ccc(NC)cc2O1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
HPGD P15428 2/20 0.37
RAB9A P51151 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2C9 P11712 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KIF11 P52732 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24441074 0.77 KDM4E (0.35) SMN1; SMN2ALDH1A1TP53MAPTNPSR1
SCHEMBL25839890 0.75 NPC1 (0.37) NPC1HPGDRAB9ACYP1A2CYP2C19
SCHEMBL27435456 0.75 PTGS1 (0.35) ALDH1A1ALOX15ALOX12
SCHEMBL14626209 0.73 KIF11 (0.47) NPC1HPGDRAB9ACYP1A2CYP2C19
SCHEMBL3359576 0.73 KIF11 (0.47) NPC1RAB9ASMN1; SMN2KIF11ALDH1A1
Hydrochloric Acid SCHEMBL20502848 0.72 KIF11 (0.46) NPC1RAB9ASMN1; SMN2KIF11ALDH1A1
SCHEMBL24218323 0.67 POLB (0.58) NPC1HPGDRAB9ACYP1A2CYP2C19
SCHEMBL28417969 0.64 ODC1 (0.45) NPC1HPGDRAB9ASMN1; SMN2ALDH1A1
SCHEMBL28891111 0.62 MAPT (0.38) ALDH1A1TP53MAPTNPSR1ALOX12
SCHEMBL28405015 0.61 HIF1A (0.50) NPC1HPGDRAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024126117-A1 PYRIMIDINONE DERIVATIVES AS PESTICIDAL COMPOUNDS BASF SE (DE) 2024-06-20 WO disclosed