Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486507 | 0.92 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4CTSB | |
| SCHEMBL27433911 | 0.86 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7566874 | 0.80 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4CTSB | |
| SCHEMBL7566388 | 0.79 | GRIA1 (0.49) | GRIA1GRIA2GRIA3GRIA4L3MBTL1 | |
| SCHEMBL27457814 | 0.77 | BCL9 (0.38) | GRIA1GRIA2GRIA3GRIA4TDP1 | |
| SCHEMBL27459486 | 0.73 | GRIA1 (0.38) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8660079 | 0.71 | ALDH1A1 (0.39) | CTSBTDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL8660076 | 0.71 | ALDH1A1 (0.39) | CTSBTDP1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL27546229 | 0.71 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27434788 | 0.64 | BCL9 (0.31) | BCL9CTNNB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125818-C | Amino acid derivatives of substituted quinoxaline 2, 3 -dione derivativesa as glutamate receptor antagonists | WARNER LAMBERT CO (US) | 2003-10-29 | — | — | CN | disclosed |
| CN-1187190-A | Amino acid derivatives of substituted quinoxaline 2, 3-dione derivatives as glutamate receptor antagonists | WARNER LAMBERT CO (US) | 1998-07-08 | — | — | CN | disclosed |