Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27433911 | 0.87 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27486507 | 0.75 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27436503 | 0.73 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27546229 | 0.70 | GRIA1 (0.33) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7566874 | 0.65 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7566004 | 0.60 | GRIA1 (0.43) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL3669653 | 0.57 | POLB (0.35) | — | |
| SCHEMBL11838143 | 0.56 | — | — | |
| SCHEMBL897597 | 0.55 | LMNA (0.33) | — | |
| SCHEMBL9118222 | 0.55 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125818-C | Amino acid derivatives of substituted quinoxaline 2, 3 -dione derivativesa as glutamate receptor antagonists | WARNER LAMBERT CO (US) | 2003-10-29 | — | — | CN | disclosed |