Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Propane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL17183875 | 0.87 | TSHR (0.50) | — | |
| Alcohol SCHEMBL20295436 | 0.87 | TSHR (0.50) | — | |
| Butane SCHEMBL27419033 | 0.87 | CA2 (0.44) | — | |
| Butane SCHEMBL8098393 | 0.87 | — | — | |
| SCHEMBL1043227 | 0.87 | CA2 (0.44) | — | |
| Alcohol SCHEMBL282048 | 0.87 | — | — | |
| Sulfuric Acid SCHEMBL6072236 | 0.86 | CA5A (0.60) | — | |
| Sulfuric Acid SCHEMBL126251 | 0.86 | — | — | |
| SCHEMBL25599 | 0.85 | CA2 (0.58) | — | |
| SCHEMBL8596055 | 0.85 | CA2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220288285-A1 | CATIONIC NANODRUG, PREPARATION METHOD THEREFOR, AND DRUG-LOADED IMPLANTABLE MEDICAL DEVICE | SHANGHAI MICROPORT MEDICAL (GROUP) CO., LTD. (CN) | 2022-09-15 | — | — | US | claimed |
| EP-4026536-A1 | CATIONIC NANODRUG, PREPARATION METHOD THEREFOR, AND DRUG-LOADED IMPLANTABLE MEDICAL DEVICE | Shanghai MicroPort Medical (Group) Co., Ltd. (CN) | 2022-07-13 | — | — | EP | claimed |
| US-20220288285-A1 | CATIONIC NANODRUG, PREPARATION METHOD THEREFOR, AND DRUG-LOADED IMPLANTABLE MEDICAL DEVICE | SHANGHAI MICROPORT MEDICAL (GROUP) CO., LTD. (CN) | 2022-09-15 | — | — | US | disclosed |
| EP-4026536-A1 | CATIONIC NANODRUG, PREPARATION METHOD THEREFOR, AND DRUG-LOADED IMPLANTABLE MEDICAL DEVICE | Shanghai MicroPort Medical (Group) Co., Ltd. (CN) | 2022-07-13 | — | — | EP | disclosed |
| CN-102892765-B | Cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL SA | 2015-04-29 | — | — | CN | disclosed |
| CN-102892765-A | Novel cyclohexylamine derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonist activity | ALMIRALL SA | 2013-01-23 | — | — | CN | disclosed |
| CN-1125943-A | Diimide polycyclic and heterocyclic chromophores as antitumor agents | DU PONT MERCK PHARMA (US) | 1996-07-03 | — | — | CN | disclosed |