Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430459 | 1.00 | MCOLN3 (0.56) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL1828638 | 0.85 | MAPT (0.51) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL7536109 | 0.83 | CA2 (0.46) | MCOLN3CRHBPCRHR2ALDH1A1HTT | |
| SCHEMBL10700954 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL29397077 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL994972 | 0.83 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL3813276 | 0.82 | VCAM1 (0.50) | ALDH1A1TSHRCYP3A4HTTKDM4E | |
| SCHEMBL731102 | 0.81 | MCOLN3 (0.60) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL6039257 | 0.81 | MCOLN3 (0.56) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL1156340 | 0.81 | CA2 (0.66) | MCOLN3CRHBPCRHR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420495-A | Method for continuously preparing 3-nitro-4-methylbenzenesulfonyl chloride | 金华双宏化工有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-116589384-A | Method for synthesizing 3-nitro-4-methylbenzenesulfonyl chloride by utilizing microchannel reactor | 贵州微化科技有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| JP-58118558-A | — | — | None | — | — | JP | disclosed |
| JP-58219159-A | — | — | None | — | — | JP | disclosed |
| US-20250223266-A1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2025-07-10 | — | — | US | disclosed |
| CN-119930484-A | Synthesis method of 4-methylsulfonyl toluene derivative | 辽宁龙田化工科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-12129236-B2 | PARG inhibitory compounds | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-10-29 | — | — | US | disclosed |
| CN-112979631-B | PARG inhibiting compounds | 癌症研究科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118420495-A | Method for continuously preparing 3-nitro-4-methylbenzenesulfonyl chloride | 金华双宏化工有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-118420495-A | Method for continuously preparing 3-nitro-4-methylbenzenesulfonyl chloride | 金华双宏化工有限公司 | 2024-08-02 | — | — | CN | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4229372-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4189486-A | FUNGICIDES | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4155931-A | COMPLEMENT INHIBITORS FOR MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4060549-A | Process for preparing sulfonic acid fluorides | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-29 | — | — | US | disclosed |
| US-4036838-A | Process for the production of nitro derivatives of aromatic compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12129236-B2 | PARG inhibitory compounds | PARP11, PARG, PARP16 | MCOLN3 3996/4885CRHBP 3601/4885CRHR2 3807/4885 |
| US-20250223266-A1 | PARG INHIBITORY COMPOUNDS | PARG, PARP11, PARP16 | MCOLN3 4157/4885CRHBP 3569/4885CRHR2 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.