Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.58 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397077 | 1.00 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH3A1ALDH1A1 | |
| Hydrogen Peroxide SCHEMBL28682950 | 0.96 | TSHR (0.57) | MCOLN3CRHBPCRHR2ALDH3A1ALDH1A1 | |
| SCHEMBL17347342 | 0.85 | ALDH3A1 (0.47) | MCOLN3CRHBPCRHR2ALDH3A1ALDH1A1 | |
| SCHEMBL10700954 | 0.85 | MCOLN3 (0.58) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL6516381 | 0.85 | MAPT (0.53) | MCOLN3CRHBPCRHR2ALDH3A1ALDH1A1 | |
| SCHEMBL9568265 | 0.83 | LMNA (0.60) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL1156340 | 0.83 | CA2 (0.66) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL731102 | 0.83 | MCOLN3 (0.60) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL6039257 | 0.83 | MCOLN3 (0.56) | MCOLN3CRHBPCRHR2ALDH1A1TSHR | |
| SCHEMBL30430459 | 0.83 | MCOLN3 (0.56) | MCOLN3CRHBPCRHR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497355-B2 | Process for preparation of mesotrione and its intermediates | RALLIS INDIA LIMITED (IN) | 2025-12-16 | — | — | US | claimed |
| CN-119661410-A | Preparation method of 2-nitro-4-methylsulfonyl benzoic acid | 江苏扬农化工股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119552099-A | Green synthesis method of 2-nitro-4-methylsulfonyl benzoic acid | 浙江工业大学 | 2025-03-04 | — | — | CN | claimed |
| CN-221964483-U | 2-Nitro-4-methylsulfonyl toluene solution concentration evaporator | 上虞颖泰精细化工有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-115784948-B | New method for preparing 2-nitro-4-methylsulfonyl benzoic acid by oxidizing active manganese dioxide | 嘉兴学院 | 2024-08-06 | — | — | CN | claimed |
| CN-118255699-A | Method for continuously preparing 2-nitro-4-methylsulfonyl benzoic acid | 北京颖泰嘉和生物科技股份有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-115672395-B | Catalyst system and method for preparing 2-nitro-4-methylsulfonyl benzoic acid by catalytic oxidation | 宁夏伟创药业有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-117964527-A | Method for preparing 2-nitro-4-methylsulfonyl benzoic acid by catalytic oxidation | 中国科学院兰州化学物理研究所 | 2024-05-03 | — | — | CN | claimed |
| CN-114085173-B | Preparation method of 2-nitro-4-methylsulfonyl benzaldehyde | 嘉兴学院 | 2024-04-16 | — | — | CN | claimed |
| CN-115819297-B | Preparation method of 2-nitro-4-methylsulfonyl benzoic acid | 南京先进生物材料与过程装备研究院有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-9870909-B2 | Compositions and methods for mass spectometry | MSTM, LLC | 2018-01-16 | — | — | US | claimed |
| CN-104844484-B | method for preparing 2-nitro-4-methylsulfonylbenzoic acid by catalytic oxidation of 2-nitro-4-methylsulfonyltoluene | 南京工业大学 | 2017-06-27 | — | — | CN | claimed |
| CN-104557639-B | Method of preparing 2-nitro-4-methylsulfonyl benzoic acid | 沈阳化工研究院有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106496079-A | The technique that a kind of Oxygen Catalytic Oxidation produces 2 nitro, 4 thiamphenicol benzoic acid | 华东理工大学 | 2017-03-15 | — | — | CN | claimed |
| CN-103121961-B | Synthesis method of weedicide mesotrione intermediate 2-nitro-4-mesyltoluene | JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) | 2014-10-01 | — | — | CN | claimed |
| CN-103121961-A | Synthesis method of weedicide mesotrione intermediate 2-nitro-4-mesyltoluene | JIANGSU FLAG CHEMICAL INDUSTRY CO LTD | 2013-05-29 | — | — | CN | claimed |
| CN-102584650-A | Preparation method of 2-nitro-4-methylsulphonylbenzoic acid | SINOCHEM CORP | 2012-07-18 | — | — | CN | claimed |
| US-7820863-B2 | Process for purifying Mesotrione | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-26 | — | — | US | claimed |
| CN-100378071-C | Process for purifying mesotrione | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-02 | — | — | CN | claimed |
| CN-1995014-A | Method for preparing 2-nitro-4-methyl p-tolyl sulfone using solid superstrong acid | UNIV HEILONGJIANG (CN) | 2007-07-11 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497355-B2 | Process for preparation of mesotrione and its intermediates | COMT, NDUFS3, NDUFS7 | MCOLN3 1125/4885CRHBP 1265/4885CRHR2 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.