Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22493445 | 0.82 | SIGMAR1 (0.49) | MEN1KMT2AADRB3HTTSMN1; SMN2 | |
| SCHEMBL26050037 | 0.79 | ADRB2 (0.55) | ALDH1A1KDM4EMEN1KMT2AADRB3 | |
| SCHEMBL9973127 | 0.76 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL28661867 | 0.75 | SMN1; SMN2 (0.65) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9973180 | 0.71 | MAPT (0.70) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL22222297 | 0.70 | KMT2A (0.66) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL6469311 | 0.69 | SMN1; SMN2 (0.57) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4614753 | 0.69 | MEN1 (0.71) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL22493446 | 0.69 | HRH4 (0.33) | — | |
| SCHEMBL9921415 | 0.68 | MAPT (0.59) | MAPTMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137506-A1 | COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS | CURASEN THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |