SCHEMBL22493446

SCHEMBL22493446

Cc1ncc(F)cc1CCNC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ HRH4 Q9H3N8 2/20 0.33
▸ HRH3 Q9Y5N1 2/20 0.33
▸ AGBL2 Q5U5Z8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22493447 0.81 HRH4 (0.33) HRH4HRH3
SCHEMBL26859257 0.71 LMNA (0.35) HRH4HRH3
SCHEMBL17553820 0.71 AGBL2 (0.42) AGBL2
SCHEMBL22455139 0.70 NOS1 (0.39) HRH4HRH3
SCHEMBL29721716 0.70 DAO (0.40) HRH4HRH3
SCHEMBL22493402 0.70 P2RX7 (0.37) —
SCHEMBL29721743 0.70 NOS1 (0.39) HRH4HRH3
SCHEMBL4143222 0.70 ALDH1A1 (0.46) AGBL2
SCHEMBL27437070 0.69 ALDH1A1 (0.45) —
SCHEMBL22864224 0.69 SLC40A1 (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024137506-A1 COMPOSITIONS AND METHODS FOR IMPROVING NEUROLOGICAL DISEASES AND DISORDERS CURASEN THERAPEUTICS, INC. (US) 2024-06-27 — — WO disclosed
WO-2023225021-A1 COMPOSITIONS AND METHODS FOR TREATING PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS (ALS) CURASEN THERAPEUTICS, INC. (US) 2023-11-23 — — WO disclosed
WO-2020198466-A9 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. (US) 2020-12-30 — — WO disclosed
WO-2020198466-A1 BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME CURASEN THERAPEUTICS, INC. (US) 2020-10-01 — — WO disclosed
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