Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 9/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743717 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4TRPV1NLRP3MEN1 | |
| SCHEMBL2743840 | 0.92 | CHRM2 (0.54) | CHRM2CHRM4TRPV1MEN1ALDH1A1 | |
| SCHEMBL30323644 | 0.78 | CHRM2 (0.46) | CHRM2CHRM4TRPV1MEN1ALDH1A1 | |
| SCHEMBL1428735 | 0.78 | RORC (0.51) | RORCHRH3DRD2DRD4DRD3 | |
| SCHEMBL2754109 | 0.78 | MEN1 (0.38) | MEN1ALDH1A1KMT2ARORCHRH3 | |
| SCHEMBL30323705 | 0.78 | MEN1 (0.38) | MEN1ALDH1A1KMT2ARORCHRH3 | |
| SCHEMBL1394587 | 0.77 | RORC (0.50) | RORCHRH3DRD2DRD4DRD3 | |
| SCHEMBL917255 | 0.76 | DRD2 (0.57) | CHRM2CHRM4MEN1ALDH1A1KMT2A | |
| SCHEMBL4400467 | 0.73 | CHRM2 (0.61) | CHRM2CHRM4TRPV1MEN1ALDH1A1 | |
| SCHEMBL6684778 | 0.73 | CHRM2 (0.52) | CHRM2CHRM4TRPV1HRH3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49362-E1 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
| US-8178360-B2 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-05-15 | — | — | US | disclosed |
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-01-14 | — | — | US | disclosed |
| EP-2021415-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | Solexa Limited (GB) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007135368-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | SOLEXA LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | HNRNPH3, DDB1, CD99 | CHRM2 4670/4885CHRM4 4183/4885TRPV1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.