Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 5/20 | 0.38 |
| ▸ | DRD5 | P21918 | 5/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743717 | 0.92 | CHRM2 (0.47) | CHRM2CHRM4TRPV1DRD2DRD4 | |
| SCHEMBL2743718 | 0.92 | CHRM2 (0.47) | CHRM2CHRM4TRPV1DRD2DRD4 | |
| SCHEMBL1428735 | 0.83 | RORC (0.51) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL917255 | 0.82 | DRD2 (0.57) | CHRM2CHRM4DRD2DRD4DRD3 | |
| SCHEMBL1394587 | 0.82 | RORC (0.50) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL30323644 | 0.81 | CHRM2 (0.46) | CHRM2CHRM4TRPV1DRD2DRD4 | |
| SCHEMBL9816060 | 0.78 | HDAC1 (0.47) | CHRM2CHRM4DRD2DRD4DRD3 | |
| SCHEMBL19365230 | 0.78 | CHRM2 (0.53) | CHRM2CHRM4TRPV1DRD2DRD4 | |
| SCHEMBL10411259 | 0.78 | HDAC1 (0.49) | CHRM2CHRM4DRD2DRD4DRD3 | |
| SCHEMBL4503966 | 0.77 | CHRM2 (0.58) | CHRM2CHRM4TRPV1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49362-E1 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
| US-RE49362-E1 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2023-01-10 | — | — | US | disclosed |
| EP-2021415-B1 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | ILLUMINA CAMBRIDGE LTD (GB) | 2017-03-15 | — | — | EP | disclosed |
| EP-2021415-B1 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | ILLUMINA CAMBRIDGE LTD (GB) | 2017-03-15 | — | — | EP | disclosed |
| US-8178360-B2 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-05-15 | — | — | US | disclosed |
| US-8178360-B2 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-05-15 | — | — | US | disclosed |
| US-8178360-B2 | Dye compounds and the use of their labelled conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-05-15 | — | — | US | disclosed |
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-01-14 | — | — | US | disclosed |
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-01-14 | — | — | US | disclosed |
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-01-14 | — | — | US | disclosed |
| WO-2007135368-A2 | DYE COMPOUNDS AND THE USE OF THEIR LABELLED CONJUGATES | SOLEXA LIMITED (GB) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009353-A1 | Dye Compounds and the Use of their Labelled Conjugates | HNRNPH3, DDB1, CD99 | CHRM2 4670/4885CHRM4 4183/4885TRPV1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.