Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 8/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 8/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 8/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | GMPS | P49915 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669003 | 0.71 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6045783 | 0.69 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL23969763 | 0.67 | PI4K2A (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL439243 | 0.66 | SLC28A1 (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL29799646 | 0.66 | SLC28A1 (0.56) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL27438888 | 0.66 | PI4KA (0.67) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL7738504 | 0.66 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL4745239 | 0.64 | PI4K2A (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL6045856 | 0.64 | PI4K2A (0.49) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22460509 | 0.64 | PI4K2A (0.52) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1125946-A | Novel carbocyclic nucleoside agents useful as selective inhibitors of proinflammatory cytokines | MERRELL DOW PHARMA (US) | 1996-07-03 | — | — | CN | disclosed |