Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28516773 | 1.00 | HPGD (0.49) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL14457242 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL925960 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL9977242 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| Methyl Alcohol SCHEMBL72605 | 0.93 | HSD17B10 (0.49) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL27443087 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27439612 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27516238 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL5246013 | 0.84 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27720507 | 0.84 | HPGD (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582482-B | Pharmaceutically active disubstituted triazine derivatives | 利德探索中心有限公司 | 2016-10-12 | — | — | CN | disclosed |