Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100905 | 1.00 | HPGD (0.49) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL14457242 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL925960 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL9977242 | 0.95 | HSD17B10 (0.50) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| Methyl Alcohol SCHEMBL72605 | 0.93 | HSD17B10 (0.49) | HPGDEPHX1HSD17B10SMN1; SMN2USP2 | |
| SCHEMBL27443087 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27439612 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27516238 | 0.88 | HSD17B10 (0.42) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL5246013 | 0.84 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27720507 | 0.84 | HPGD (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858874-A | HPK1 degrading agents, compositions comprising the same, and methods of use thereof | 百放开曼有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-112939848-B | Preparation method of bupivacaine and intermediate (S) -2-piperidinecarboxylic acid thereof | 浙江工业大学 | 2022-07-01 | — | — | CN | disclosed |
| CN-111995565-B | Preparation method of (S) -2-piperidinecarboxylic acid | 浙江工业大学 | 2022-01-25 | — | — | CN | disclosed |
| CN-112979537-A | Preparation method of cocaine drug intermediate (S) -2-piperidinecarboxylic acid | 浙江工业大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-112939848-A | Preparation method of bupivacaine and intermediate (S) -2-piperidinecarboxylic acid thereof | 浙江工业大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-111995565-A | Preparation method of (S) -2-piperidinecarboxylic acid | 浙江工业大学 | 2020-11-27 | — | — | CN | disclosed |
| CN-101687012-A | New cyclic peptide compounds | ASTELLAS PHARMA INC | 2010-03-31 | — | — | CN | disclosed |