SCHEMBL27445177

SCHEMBL27445177

Cc1cc([N+](=O)[O-])c([N+](=O)[O-])c(C)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.47
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 4/20 0.47
RECQL P46063 2/20 0.47
CYP1A2 P05177 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 5/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6671674 0.85 CYP1A2 (0.52) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL5202894 0.85 CYP1A2 (0.52) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL3606399 0.84 ALDH1A1 (0.43) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL6156643 0.82 ALDH1A1 (0.46) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL1828688 0.82 ALDH1A1 (0.48) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL7527476 0.82 CYP1A2 (0.52) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL2581014 0.82 CYP1A2 (0.57) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL5203798 0.81 CYP1A2 (0.56) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL304097 0.78 CYP1A2 (0.57) TSHRALDH1A1CYP3A4RECQLCYP1A2
SCHEMBL13176886 0.77 HTT (0.44) TSHRALDH1A1CYP3A4RECQLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1099279-A Artificial musk serial anti-inflammatory and anticancer compound Chinese patent medicine and making process thereof BEIFANG MEDICINE DEVEL INST ZU (CN) 1995-03-01 CN disclosed