Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200474 | 0.80 | ALOX5 (0.63) | ALOX5MTNR1ATHRATHRBPTPN1 | |
| SCHEMBL27463101 | 0.79 | ALOX5 (0.55) | ALOX5MTNR1ATHRATHRBMTNR1B | |
| SCHEMBL27445498 | 0.78 | ALOX5 (0.61) | ALOX5MTNR1ATHRATHRBPTPN1 | |
| SCHEMBL7203574 | 0.78 | ALOX5 (0.66) | ALOX5MTNR1AMTNR1BNR5A1 | |
| SCHEMBL7198793 | 0.78 | ALOX5 (0.66) | ALOX5MTNR1ATSHR | |
| SCHEMBL27461740 | 0.78 | ALOX5 (0.54) | ALOX5MTNR1ATHRATHRBMTNR1B | |
| SCHEMBL7202221 | 0.77 | ALOX5 (0.56) | ALOX5MTNR1ATHRATHRBMTNR1B | |
| SCHEMBL9729696 | 0.76 | ALOX5 (0.58) | ALOX5MTNR1ATHRATHRBMTNR1B | |
| SCHEMBL9730115 | 0.74 | ALOX5 (0.64) | ALOX5MTNR1AMTNR1BNR5A1 | |
| SCHEMBL7199698 | 0.71 | MTNR1A (0.72) | ALOX5MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1139584-C | Heterocyclic compounds, method for preparing and medicine compositions containing same | ɪά��ʵ���� | 2004-02-25 | — | — | CN | disclosed |