Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202221 | 0.99 | ALOX5 (0.56) | ALOX5THRATHRBMTNR1AMTNR1B | |
| SCHEMBL9729572 | 0.81 | ALOX5 (0.60) | ALOX5MAOB | |
| SCHEMBL8627404 | 0.79 | MAOB (0.57) | ALOX5MTNR1AMAOBTP53 | |
| SCHEMBL27463101 | 0.79 | ALOX5 (0.55) | ALOX5THRATHRBMTNR1AMTNR1B | |
| Formamide SCHEMBL9729689 | 0.78 | ALOX5 (0.63) | ALOX5MTNR1AMTNR1B | |
| SCHEMBL7198793 | 0.78 | ALOX5 (0.66) | ALOX5MTNR1ATSHR | |
| SCHEMBL7200474 | 0.78 | ALOX5 (0.63) | ALOX5THRATHRBMTNR1A | |
| SCHEMBL7203574 | 0.78 | ALOX5 (0.66) | ALOX5MTNR1AMTNR1BNR5A1 | |
| SCHEMBL27461740 | 0.78 | ALOX5 (0.54) | ALOX5THRATHRBMTNR1AMTNR1B | |
| SCHEMBL9729518 | 0.77 | ALOX5 (0.59) | ALOX5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155130-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0412939-A2 | Certain benzopyran and benzothiopyran derivatives | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |