Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.83 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193735 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL29624606 | 0.91 | KDM4E (1.00) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL9388988 | 0.80 | KDM4E (0.79) | KDM4EALDH1A1HPGDMAPK1HTT | |
| L-Threonic Acid SCHEMBL22469954 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL31343793 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL14829872 | 0.77 | KDM4E (0.64) | KDM4EALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL8729784 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL30172555 | 0.75 | KDM4E (0.63) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL31376496 | 0.75 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDMAPK1HTT | |
| SCHEMBL9724160 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118456-C | 1,2-dihydro-2-oxoquinoline derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-08-20 | — | — | CN | disclosed |
| CN-1280569-A | 1, 2-dihydro-2-oxoquinoline derivative | TAISHO PHARMACEUTICAL CO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |