SCHEMBL27445681

SCHEMBL27445681

CCCC(=O)NS(=O)(=O)C(F)(F)C(F)(F)C(C)(F)F

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
CA1 P00915 6/20 0.36
CA2 P00918 6/20 0.36
MMP1 P03956 5/20 0.36
MMP2 P08253 5/20 0.36
MMP9 P14780 5/20 0.36
MMP8 P22894 5/20 0.36
MMP13 P45452 5/20 0.36
CTSD P07339 1/20 0.35
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
CASP2 P42575 1/20 0.31
GSK3B P49841 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24028212 0.85 HDAC3 (0.35) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL24028729 0.82 CA1 (0.33) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL25902897 0.81 CA1 (0.37) CA1CA2MMP1MMP2MMP9
SCHEMBL7240710 0.80 HDAC3 (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL13366822 0.77 HDAC3 (0.44) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL24990010 0.73 CA1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL24059246 0.71 ALDH1A1 (0.32) CA1CA2CA12CA9ALDH1A1
SCHEMBL26445911 0.71 CA1 (0.36) CA1CA2MMP1MMP2MMP9
SCHEMBL26042710 0.70 CA1 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL25467911 0.69 CYP19A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12032288-B2 Actinic ray-sensitive or radiation-sensitive resin composition, resist film, pattern forming method, and method for manufacturing electronic device RER1, COL1A1, RAD51 HDAC3 4727/4885HDAC1 3068/4885HDAC2 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.