Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 5/20 | 0.39 |
| ▸ | CDK1 | P06493 | 5/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445903 | 0.79 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2APAF1CDK1CASP3 | |
| SCHEMBL22650407 | 0.70 | L3MBTL1 (0.37) | L3MBTL1SMN1; SMN2APAF1CDK1TDP1 | |
| SCHEMBL22650503 | 0.70 | MAPK14 (0.46) | L3MBTL1SMN1; SMN2CDK1CDK5CDK5R1 | |
| SCHEMBL22650721 | 0.68 | SMN1; SMN2 (0.34) | L3MBTL1SMN1; SMN2CDK5CDK5R1CDK2 | |
| SCHEMBL10235442 | 0.68 | HCAR3 (0.41) | L3MBTL1SMN1; SMN2APAF1CDK2MAPT | |
| SCHEMBL15763397 | 0.67 | CDK1 (0.47) | CDK1TDP1CDK5CDK5R1CCNB1 | |
| SCHEMBL22700168 | 0.66 | CDK2 (0.51) | CDK1TDP1CDK5CDK5R1CCNB1 | |
| SCHEMBL12451372 | 0.66 | CDK1 (0.67) | CDK1TDP1CCNB1CCNE1CDK2 | |
| SCHEMBL31380703 | 0.66 | CDK2 (0.51) | CDK1TDP1CDK5CDK5R1CCNB1 | |
| SCHEMBL24916023 | 0.65 | BCL2L11 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |