Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.35 |
| ▸ | CDK2 | P24941 | 7/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 3/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650403 | 0.87 | MAPK14 (0.35) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL22650503 | 0.86 | MAPK14 (0.46) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL22650600 | 0.83 | MAPK14 (0.40) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL29491131 | 0.83 | MAPK14 (0.40) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL29491141 | 0.83 | SMN1; SMN2 (0.37) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL22650827 | 0.80 | CDK4 (0.39) | CDK2CDK1 | |
| SCHEMBL22650721 | 0.78 | SMN1; SMN2 (0.34) | L3MBTL1SMN1; SMN2CCNA2CDK2CCNA1 | |
| SCHEMBL27445903 | 0.72 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2CDK2CDK5CDK5R1 | |
| SCHEMBL27445898 | 0.70 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2CDK2CDK5CDK5R1 | |
| SCHEMBL30038555 | 0.70 | MAPK14 (0.42) | SMN1; SMN2CDK2DYRK1AMAPK14CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040446-A | CDK inhibitors | 基因泰克公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20220296595-A1 | CDK INHIBITORS | GENENTECH, INC. | 2022-09-22 | — | — | US | disclosed |
| EP-3966213-A1 | CDK INHIBITORS | Qilu Regor Therapeutics Inc. (CN) | 2022-03-16 | — | — | EP | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220296595-A1 | CDK INHIBITORS | CDKL1, CDK9, CDK6 | L3MBTL1 2456/4885SMN1; SMN2 2350/4885CCNA2 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.