Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886297 | 0.81 | MEN1 (0.43) | MEN1KMT2APOLBLMNAKDM4E | |
| SCHEMBL7700726 | 0.73 | CYP2D6 (0.44) | ADRB2ADRB1ADRB3CYP1A2GAA | |
| Fumaric Acid SCHEMBL7700757 | 0.69 | KCNH2 (0.44) | CYP1A2CYP2C19 | |
| Fumaric Acid SCHEMBL7700761 | 0.69 | KCNH2 (0.44) | CYP1A2CYP2C19 | |
| SCHEMBL8213885 | 0.65 | RORC (0.41) | MEN1KMT2ALMNACYP1A2GAA | |
| SCHEMBL21895849 | 0.64 | MEN1 (0.54) | MEN1KMT2APOLBCYP1A2GAA | |
| SCHEMBL5159157 | 0.64 | MEN1 (0.54) | MEN1KMT2APOLBCYP1A2GAA | |
| SCHEMBL301661 | 0.64 | LMNA (0.70) | MEN1KMT2ALMNAKDM4EADRB2 | |
| SCHEMBL21837423 | 0.64 | HTR1D (0.53) | MEN1KMT2APOLBKDM4ECYP1A2 | |
| SCHEMBL21837887 | 0.64 | HTR1D (0.53) | MEN1KMT2APOLBKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1140498-C | Novel antiarrhythmic compounds | ҩ���о�Ժ������ҵ | 2004-03-03 | — | — | CN | disclosed |
| CN-1284941-A | Novel antiarrhythmic compounds | PHARMACEUTICAL RES INST PUBLIC (HU) | 2001-02-21 | — | — | CN | disclosed |