Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959696 | 1.00 | AR (0.34) | ARHTR2AHTR2C | |
| SCHEMBL8959557 | 0.82 | HTR2A (0.48) | ARHTR2AHTR2C | |
| SCHEMBL8959753 | 0.82 | HTR2A (0.48) | ARHTR2AHTR2C | |
| SCHEMBL7997832 | 0.79 | KMO (0.48) | ARHTR2AHTR2C | |
| SCHEMBL8959864 | 0.79 | HTR2A (0.49) | ARHTR2AHTR2C | |
| SCHEMBL27363223 | 0.79 | HTR2A (0.49) | ARHTR2AHTR2C | |
| SCHEMBL8959713 | 0.79 | HTR2A (0.49) | ARHTR2AHTR2C | |
| SCHEMBL8959561 | 0.79 | HTR2A (0.49) | ARHTR2AHTR2C | |
| SCHEMBL8959608 | 0.78 | HTR2A (0.45) | ARHTR2AHTR2C | |
| SCHEMBL8959562 | 0.77 | HTR2C (0.46) | ARHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1061341-C | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-31 | — | — | CN | disclosed |
| CN-1105988-A | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |