Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050847 | 0.98 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL27335768 | 0.95 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| Bis(Dimethylaminethiocarbonyl)Monosulfide SCHEMBL27974603 | 0.77 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL30987223 | 0.73 | MAPT (0.60) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL28563540 | 0.73 | MAPT (0.60) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL11600529 | 0.73 | MAPT (0.54) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL3810651 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL18410587 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL446289 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 | |
| SCHEMBL329419 | 0.70 | MAPT (0.56) | MAPTKDM4EALDH1A1HSD17B10EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131272-C | Polyimide reinforced nitile-butadiene rubber composite material | LANZHOU INST CHEMICOPHYSICS (CN) | 2003-12-17 | — | — | CN | disclosed |
| CN-1339529-A | Polyimide reinforced nitile-butadiene rubber composite material | LANZHOU CHEM PHYS INST (CN) | 2002-03-13 | — | — | CN | disclosed |