Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27451708 | 0.94 | KMT2A (0.53) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL27451205 | 0.81 | KMT2A (0.48) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL27453119 | 0.80 | KMT2A (0.45) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL27451116 | 0.79 | RAB9A (0.77) | KMT2AGAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27452585 | 0.78 | RAB9A (0.58) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL27451123 | 0.77 | RAB9A (0.68) | KMT2AGAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL27451288 | 0.76 | KMT2A (0.57) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL28608538 | 0.75 | MMP2 (0.69) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL31472989 | 0.75 | MMP2 (0.69) | KMT2ACYP1A2CYP3A4GAACYP2C9 | |
| SCHEMBL27451960 | 0.75 | PAX8 (0.54) | KMT2ACYP3A4GAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |