Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452781 | 0.87 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27451123 | 0.87 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27453018 | 0.81 | PAX8 (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27451708 | 0.81 | KMT2A (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27451116 | 0.81 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27452720 | 0.79 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27451204 | 0.78 | KMT2A (0.55) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27452496 | 0.78 | ADORA2A (0.65) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27452583 | 0.78 | HPGD (0.57) | SMN1; SMN2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL27451960 | 0.77 | PAX8 (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145662-A1 | 2-SUBSTITUTED THIAZOLE AND BENZOTHIAZOLE COMPOSITIONS AND METHODS AS DUX4 INHIBITORS | ALTAY THERAPEUTICS, INC. (US) | 2024-07-04 | — | — | WO | disclosed |