Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.63 |
| ▸ | PRKCG | P05129 | 5/20 | 0.63 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.63 |
| ▸ | PRKCB | P05771 | 4/20 | 0.63 |
| ▸ | PRKCH | P24723 | 4/20 | 0.63 |
| ▸ | PRKCI | P41743 | 4/20 | 0.63 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.63 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.63 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.63 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol SCHEMBL28352211 | 0.94 | PRKCA (0.66) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL21462215 | 0.94 | PRKCA (0.66) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL22973790 | 0.91 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL28866474 | 0.91 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL64353 | 0.91 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL7615331 | 0.91 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL20582541 | 0.89 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL29134149 | 0.89 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL10620832 | 0.89 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL1893791 | 0.89 | PRKCA (0.69) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109313176-A | For detecting the electronic device of large biological molecule | 阿克斯比尔公司 | 2019-02-05 | — | — | CN | claimed |
| CN-105126086-B | For treating the composition and method of Gaucher disease | 夏尔人类遗传性治疗公司 | 2019-05-14 | — | — | CN | disclosed |
| CN-109498812-A | HSP90 combination treatment | 索隆-基特林癌症研究协会 | 2019-03-22 | — | — | CN | disclosed |
| CN-109313176-A | For detecting the electronic device of large biological molecule | 阿克斯比尔公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109172813-A | For treating the composition and method of Gaucher disease | 夏尔人类遗传性治疗公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-102686237-B | Composition for treating Gaucher disease | 夏尔人类遗传性治疗公司 | 2018-10-19 | — | — | CN | disclosed |
| CN-103998935-B | Hsp90 combination therapy | 索隆-基特林癌症研究协会 | 2018-10-16 | — | — | CN | disclosed |
| CN-108601762-A | Inflammatory body activates inhibitor | 客乐谐控股株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-108064242-A | Anti-GITR antibodies and methods of use thereof | 阿吉纳斯公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-108024940-A | Topical skin preparations | 玫琳凯有限公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-1732004-A | Methods of using jnk inhibitor for the treatment of pain | CELGENE CORP (US) | 2006-02-08 | — | — | CN | disclosed |
| CN-1703395-A | Aryl and heteroaryl compounds and methods of modulating blood coagulation | TRANSTECH PHARMA INC (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1639153-A | Indolylmaleimide derivatives | NOVARTIS AG (CH) | 2005-07-13 | — | — | CN | disclosed |
| CN-1533400-A | Probes, system and methods for drug discovery | ����˹̩����ҩ��˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1147486-C | 4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles | - | 2004-04-28 | — | — | CN | disclosed |
| CN-1124260-C | Para retinoic acid | HOFFMANN LA ROCHE (CH) | 2003-10-15 | — | — | CN | disclosed |
| CN-1384878-A | IREN protein, its preparation and use | YEDA RES & DEV (IL) | 2002-12-11 | — | — | CN | disclosed |
| CN-1181784-A | Genes encoding lymphointerferon regulatory factor (LSIRF) polypeptides | AMGEN CANADA INC (CA) | 1998-05-13 | — | — | CN | disclosed |
| CN-1136557-A | Para retinoic acid | HOFFMANN LA ROCHE (CH) | 1996-11-27 | — | — | CN | disclosed |
| CN-1051791-A | Enzyme assay and assay kit for measuring cell activation | RUSSELL M JAFEE (US) | 1991-05-29 | — | — | CN | disclosed |