Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.62 |
| ▸ | PRKCG | P05129 | 5/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.62 |
| ▸ | PRKCB | P05771 | 4/20 | 0.62 |
| ▸ | PRKCH | P24723 | 4/20 | 0.62 |
| ▸ | PRKCI | P41743 | 4/20 | 0.62 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.62 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.62 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.62 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.62 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol SCHEMBL28866474 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27419386 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL64353 | 1.00 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27299282 | 0.98 | PRKCA (0.63) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27478115 | 0.94 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL28465138 | 0.94 | PRKCA (0.56) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27450792 | 0.93 | PRKCA (0.62) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL23610504 | 0.92 | PRKCA (0.61) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL27579226 | 0.92 | PRKCA (0.67) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL7566989 | 0.92 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777979-B1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2024-01-17 | — | — | EP | disclosed |
| CN-110974842-B | Methods of identifying compounds for treating cancer | 卡洛斯三世癌症研究中心全国基金会 | 2023-09-19 | — | — | CN | disclosed |
| CN-108478599-B | Mesenchymal stromal cells and uses related thereto | 安斯泰来再生医药协会 | 2022-08-02 | — | — | CN | disclosed |
| CN-114728026-A | Compositions comprising bacterial species and methods related thereto | 未知君有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021071292-A9 | COMPOSITION, USING LACTOBACILLUS PLANTARUM STRAIN OR LIKE, FOR ALLEVIATION OF RESPIRATORY DISEASES | 한국식품연구원 | 2021-07-22 | — | — | WO | disclosed |
| EP-3777979-A1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | Vivavision Biotech, Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |
| CN-112063624-A | SiRNA molecule for inhibiting caspase1 gene expression and application thereof | 湖南中医药大学 | 2020-12-11 | — | — | CN | disclosed |
| CN-112048509-A | siRNA molecule for inhibiting NLRP3 gene expression and application thereof | 湖南中医药大学 | 2020-12-08 | — | — | CN | disclosed |
| CN-110494549-A | By invertibity infiltration to the carrier-free Intracellular delivery of non-adherent cell | AVECTAS LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-105377226-B | Use of petroselinic acid for combating aesthetic disorders of the bodily form | 欧莱雅 | 2019-10-25 | — | — | CN | disclosed |
| CN-101573340-A | Modulators of glucocorticoid receptor AP-1 and/or NF-kB activity and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | CN | disclosed |
| CN-101528718-A | Modulators of glucocorticoid receptor and/or AP-1 and/or NF- κ B activity and uses thereof | BRISTOL MYERS SQUIBB CO (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101300355-A | Chimeric antigen containing hepatitis c virus polypeptide and Fc fragment for eliciting an immune response | VIREXX MEDICAL CORP (CA) | 2008-11-05 | — | — | CN | disclosed |
| CN-101031318-A | Cell permissivity factor of virus and its use | PHARMACIA & UPJOHN CO LTD (US) | 2007-09-05 | — | — | CN | disclosed |
| CN-1878787-A | Detection of cholesterol ozonation products | SCRIPPS RESARCH INST (US) | 2006-12-13 | — | — | CN | disclosed |
| CN-1875030-A | Ozonation products of cholesterol for the treatment and prevention of atherosclerosis and/or cardiovascular disease | SCRIPPS RES INSITTUTE (US) | 2006-12-06 | — | — | CN | disclosed |
| CN-1243093-C | NF-kB inhibition using caffeic acid phenethyl ester derivatives, capsaicin and resiniferatoxin | RESEACH & DEV FOUNDATION (US) | 2006-02-22 | — | — | CN | disclosed |
| CN-1732003-A | Methods for treating, preventing and managing macular degeneration | CELGENE CORP (US) | 2006-02-08 | — | — | CN | disclosed |
| CN-1160309-C | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | �ճ�˹�������³˹��˾ | 2004-08-04 | — | — | CN | disclosed |
| CN-1220660-A | Alkyloxyamino substituted fluorenones and their use as protein kinase cinhibitors | HOECHST MARION ROUSSEL INC (US) | 1999-06-23 | — | — | CN | disclosed |