Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659673 | 0.85 | NPSR1 (0.69) | ALDH1A1RAB9ASTAT3NPSR1NPC1 | |
| SCHEMBL2025451 | 0.84 | SLC7A5 (0.51) | ALDH1A1F2RAB9ATMPRSS6STAT3 | |
| SCHEMBL308570 | 0.84 | ALDH1A1 (0.77) | ALDH1A1RAB9ANPSR1NPC1MAPT | |
| SCHEMBL13662571 | 0.82 | L3MBTL1 (0.61) | ALDH1A1F2RAB9ATMPRSS6NPC1 | |
| SCHEMBL6081117 | 0.81 | TGM2 (0.52) | ALDH1A1RAB9ASTAT3NPSR1NPC1 | |
| SCHEMBL7934460 | 0.81 | F2 (0.50) | ALDH1A1F2RAB9ATMPRSS6SLC7A5 | |
| SCHEMBL8341341 | 0.81 | SLC7A5 (0.51) | ALDH1A1F2RAB9ATMPRSS6STAT3 | |
| SCHEMBL13605105 | 0.80 | KCNK9 (0.70) | ALDH1A1RAB9ASTAT3NPC1MAPT | |
| SCHEMBL6081279 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1F2RAB9ATMPRSS6NPC1 | |
| SCHEMBL110296 | 0.80 | SLC7A5 (0.58) | ALDH1A1STAT3SLC7A5ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1130351-C | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2003-12-10 | — | — | CN | disclosed |
| CN-1246850-A | 1,5-benzodiazepine derivatives | ZERIA PHARM CO LTD (JP) | 2000-03-08 | — | — | CN | disclosed |